CERASORB® Foam: The Ideal Scaffold for Bone Regeneration
CERASORB® Foam is a highly advanced, multiporous composite material, consisting of high-quality Type 1 Collagen and pure-phase β-TCP (β -tricalcium phosphate) granules. Since its introduction, it has quickly become a surgeon’s preferred choice in bone regeneration procedures. CERASORB® Foam stands out due to its unique design and innovative approach to regenerative medicine, making it essential for modern bone grafting and healing.
The Ideal Scaffold by Design
A Closer Look at its 3-dimensional Bone Regeneration Capabilities
CERASORB® Foam is recognized as the “Ideal Scaffold” due to its advanced 3-dimensional collagen matrix structure, which replicates the natural extracellular matrix (ECM) of bone tissue[1]. This design promotes regeneration by supporting cellular infiltration, vascularization, and tissue integration.
1. High-Quality Type-1 Collagen: A Key Factor in Bone Regeneration
Type 1 Collagen plays a crucial role in bone healing by supporting the adhesion of mesenchymal stem cells (MSCs), which are essential for bone regeneration. The process unfolds as follows:
2. Pure-Phase β-TCP in Foam: The Highest Purity in the World
β-TCP is a proven osteoconductive material that supports bone growth.
curasan AG produces the highest purity >99% β-TCP granules, ensuring biocompatibility and osteoconductivity. These granules gradually resorb, facilitating natural bone replacement and providing sustained support during healing.
3. 3-dimensional Structure
The 3-dimensional structure of CERASORB® Foam optimizes osteogenesis. Its open, interconnected pores facilitate cell migration, blood vessel infiltration, and nutrient diffusion creating an ideal environment for bone formation.
4. Biocompatibility and Bioactivity
CERASORB® Foam is well-tolerated by the human body, minimizing inflammatory responses and reducing complications. Its bioactivity and hydrophilicity support new bone formation by interacting seamlessly with the surrounding tissue.
5. Versatility in Application
CERASORB® Foam is suitable for various bone regeneration procedures in the context of orthopedic surgeries. It comes in moldable and flexible forms for orthopedic applications, offering versatility for surgeons globally.
Conclusion: A New Era in Bone Regeneration
The combination of Type 1 Collagen and β-TCP granules, along with CERASORB® Foam‘s 3-dimensional structure, makes it an effective material for bone regeneration. Its design enhances cellular infiltration, osteoconduction, and vascularization while ensuring an optimal balance of support and resorption.
CERASORB® Foam remains a reliable choice for surgeons seeking predictable outcomes in bone regeneration.
[1] Lin, X., Patil, S., Gao, Y. G., & Qian, A. (2020). The bone extracellular matrix in bone formation and regeneration. Frontiers in pharmacology, 11, 757.