Epi-Guide is indicated for use as an adjunct to periodontal restorative surgeries in the treatment of periodontal defects following established surgical procedures.
High-tech Architecture — Maintains Space / Helps Arrest Epithelial Migration
Synthetic Construction — Avoid Risks of Disease from Biological Products
Completely Resorbable — Second Surgery Unnecessary to Remove Membranes
Visible Healing in Your Patients
- Forms a natural barrier to promote soft-tissue healing.
- Maintains architecture and structural integrity for up to 20 weeks after implantation.
- Complete bioresorption occurs between 6 and 12 months.
- Regenerates tissue despite flap recession or if primary closure is not obtained.
The Epi-Guide Bioresorbable Barrier Matrix is a membrane designed for use as an adjunct to periodontal restorative surgeries and assists in the regeneration of bone and periodontal support tissues. It is a porous, three-dimensional matrix fabricated from D, D-L, L polylactic acid, a bioresorbable polymer with a long history of safe medical use. The barrier’s three-layer construction is deigned to attract, trap, and retain fibroblasts and epithelial cells while maintaining space around teeth for development of bone and periodontal support tissues. The Epi-Guide maintains its architecture and structural integrity for 20 weeks after implantation with complete bioresorption between 6-12 months.
The Epi-Guide Barrier is a hydrophilic membrane that quickly absorbs blood fluid and clinical investigations have revealed that, once implanted in the body, Epi-Guide functions to support the initial blood clot and maintain competence of collateral circulation. Should the barrier become exposed or if primary closure is not obtained, clotted blood within the barrier provides a natural matrix which allows tissue to quickly grow and cover most exposures. The Epi-Guide Barrier is self-supporting and can be used in many situations without support from bone grafting materials.Layer 3: Gingival Interface
Numerous voids and intercommunicating pathways enhance fibroblast infiltration and cell attachment.
Layer 2: Inner Surface
Inner labyrinth creates pathways, while internal chambers enable collateral circulation and flow of interstitial fluid in the membrane.
Layer 1: Defect Interface
Limited porosity supports an uptake of fluid, helps adherence to the tooth surface, and inhibits fibroblast movement.
Fronds of connective tissue continue to penetrate the Epi-Guide Barrier and display collagen fiber formation. The barrier remains functional despite initiation of the resorption process. Surrounding connective tissue is normal in appearance.
EpiGuide Placement Guide
Place the Epi-Guide, smooth side towards the defect. Ensure the membrane covers the entire defect.
Epi-Guide preserves the space around the teeth for development of bone and periodontal support tissues. It maintains architecture and structural integrity for 20 weeks after implantation with complete bioresorption occuring in 6 to 12 months.
Epi-Guide comes in a sterilized 18 × 30 mm single mebrane sheet ready for easy specialized shaping. The sterile sheet resides in an outer package protected for shipping.
|Product Code||Product Name|
|50600-02||Epi-Guide 18mm x 30mm|
Maufactured by Kensey Nash Corp.
|Hermann, 2007: Clinical Observations on the New Epi-Guide® Barrier Matrix in Periodontological and Implantological Indications||Download|
|Vernino et al, 1995: Ridge Preservation of Dentition With Severe Periodontitis||Download|
|Vernino et al, 1998: Use of Biodegradable Polylactic Acid Barrier Materials in the Treatment of Grade II Periodontal Furcation Defects in Humans, Part I||Download|
|Vernino et al, 1998: Use of Biodegradable Polylactic Acid Barrier Materials in the Treatment of Grade II Periodontal Furcation Defects in Humans, Part II||Download|
|Yang, Lee, Vernino, 2000: Ridge Preservation of Dentition With Severe Periodontitis||Download|